Open connectome laboratory

Real fly and worm brains, running live in your browser.

Every neuron and synapse of a fruit fly brain and a worm has been mapped. Here those wiring diagrams taste sugar, escape shadows, fly through gusts and even play poker, and each result is shown next to rewired brains, so you can see what the real wiring does.

14
experiments in the browser
138,639
neurons in the full fly brain
4
circuits compared on every task
Rendered from the live simulation: the FlyWire escape circuit sees a looming disc and the Giant Fiber fires.

Where do you want to start?

Four ways into the same library of real circuits.

How every experiment works

  1. 1

    Senses drive real neurons

    A looming disc drives the fly's looming detectors, sugar its taste neurons, a gust its motion sensing HS cells.

  2. 2

    The measured wiring does the rest

    Spikes travel through every synapse mapped by electron microscopy to the descending neurons that command the body.

  3. 3

    The same task on control brains

    Rewired, random and silenced circuits run the same task. Only a difference from them says the wiring matters.

Research landscape

Who else runs connectomes, and where this lab fits

Eon Systems' embodied fly, flybench, webgpu-fly, OpenWorm, Cortical Labs and more, compared.

Community

33 projects by others, credited

Fly Dino, Swat, the Beat Saber fly and more, with their authors and code. Build your own experiment and share it.